Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dcctm1.1Nki
Name:	DCC netrin 1 receptor; targeted mutation 1.1, The Netherlands Cancer Institute
MGI ID:	MGI:5308795
Synonyms:	DccD23
Gene:	Dcc  Location: Chr18:71386705-72484140 bp, - strand  Genetic Position: Chr18, 45.24 cM
Alliance:	Dcctm1.1Nki page

Germline Transmission:	Earliest citation of germline transmission: J:181090
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 23 was flanked by loxP sites. The neomycin selection cassette was excised in vitro. Exon 23 was excised as well by cre expression. (J:181090)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dcc Mutation:	76 strains or lines available

Original:	J:181090 Krimpenfort P, et al., Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours. Nature. 2012 Feb 23;482(7386):538-41
All:	2 reference(s)