Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc4a5tm1.1Boet
Name:	solute carrier family 4, sodium bicarbonate cotransporter, member 5; targeted mutation 1, Thomas Boettger
MGI ID:	MGI:5306980
Synonyms:	Slc4a5delta7
Gene:	Slc4a5  Location: Chr6:83196810-83281927 bp, + strand  Genetic Position: Chr6, 35.94 cM
Alliance:	Slc4a5tm1.1Boet page

Germline Transmission:	Earliest citation of germline transmission: J:180608
Parent Cell Line:	MPI-II (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed the neo cassette. A quantitative mass-spectroscopy-based proteomic approach (SILAC-MS) confirmed the absence of protein expression. (J:180608)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc4a5 Mutation:	51 strains or lines available

Original:	J:180608 Groger N, et al., Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis. Hum Mol Genet. 2012 Mar 1;21(5):1025-36
All:	2 reference(s)