Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddntm1Ktry
Name:	dendrin; targeted mutation 1, Karl Tryggvason
MGI ID:	MGI:5301891
Gene:	Ddn  Location: Chr15:98701663-98705806 bp, - strand  Genetic Position: Chr15, 54.69 cM
Alliance:	Ddntm1Ktry page

Germline Transmission:	Earliest citation of germline transmission: J:178223
Parent Cell Line:	F1H4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NTac)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding region was replaced with an EGFP-loxP-Ub1-Em7-Neo-loxP. Immunohistochemistry confirmed the absence of protein expression. (J:178223, J:211125)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddn Mutation:	16 strains or lines available

Original:	J:178223 Yaddanapudi S, et al., CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Invest. 2011 Oct 3;121(10):3965-80
All:	3 reference(s)