Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptpmt1tm1.2Jedi
Name:	protein tyrosine phosphatase, mitochondrial 1; targeted mutation 1.2, Jack E Dixon
MGI ID:	MGI:5291922
Gene:	Ptpmt1  Location: Chr2:90741057-90748395 bp, - strand  Genetic Position: Chr2, 50.44 cM, cytoband E1
Alliance:	Ptpmt1tm1.2Jedi page

Germline Transmission:	Earliest citation of germline transmission: J:176087
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette and exons 1 and 2. (J:176087)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptpmt1 Mutation:	12 strains or lines available

Original:	J:176087 Zhang J, et al., Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 8;13(6):690-700
All:	1 reference(s)