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Mkxtm1.2Jian
Targeted Allele Detail
Summary
Symbol: Mkxtm1.2Jian
Name: mohawk homeobox; targeted mutation 1.2, Rulang Jiang
MGI ID: MGI:5287572
Synonyms: Mkx-
Gene: Mkx  Location: Chr18:6934966-7004779 bp, - strand  Genetic Position: Chr18, 4.53 cM
Alliance: Mkxtm1.2Jian page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175747
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre-mediated recombination removed exon 3 from Mkxtm1.1Jian. (J:175747)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mkx Mutation:  27 strains or lines available
References
Original:  J:175747 Liu W, et al., The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory