Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gabra2tm2.2Uru
Name:	gamma-aminobutyric acid type A receptor subunit alpha 2; targeted mutation 2.2, Uwe Rudolph
MGI ID:	MGI:5140554
Gene:	Gabra2  Location: Chr5:71115735-71253192 bp, - strand  Genetic Position: Chr5, 37.59 cM
Alliance:	Gabra2tm2.2Uru page

Germline Transmission:	Earliest citation of germline transmission: J:173378
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombinationv (induced by EIIa-cre) removed exon 5 from Gabra2tm2.1Uru. The absence of transcript expression was confirmed by qRT-PCR. (J:173378)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gabra2 Mutation:	34 strains or lines available

Original:	J:173378 Witschi R, et al., Presynaptic {alpha}2-GABAA Receptors in Primary Afferent Depolarization and Spinal Pain Control. J Neurosci. 2011 Jun 1;31(22):8134-8142
All:	10 reference(s)