Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pik3c3tm1.1Fawa
Name:	phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1.1, Fan Wang
MGI ID:	MGI:4941351
Gene:	Pik3c3  Location: Chr18:30405800-30481179 bp, + strand  Genetic Position: Chr18, 17.41 cM
Alliance:	Pik3c3tm1.1Fawa page

Germline Transmission:	Earliest citation of germline transmission: J:169569
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 17, and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 18. The frt sites were mutated and could not be used to remove the neo cassette, which remains intact. Cre mediated recombination removed the floxed region. (J:169569)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3c3 Mutation:	45 strains or lines available

Original:	J:169569 Zhou X, et al., The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation. PLoS One. 2011;6(1):e16358
All:	1 reference(s)