Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Clec1btm1.1Ksi Name: C-type lectin domain family 1, member b; targeted mutation 1.1, Katsue Suzuki-Inoue MGI ID: MGI:4839037 Gene: Clec1b  Location: Chr6:129374260-129382376 bp, + strand  Genetic Position: Chr6, 63.3 cM, cytoband F3 Alliance: Clec1btm1.1Ksi page

Lymphatic function is impaired in Clec1btm1.1Ksi/Clec1btm1.1Ksi embryos Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:165898
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Cre mediated recombination removed part of exon 1 while leaving the neo cassette intact. (J:165898)

Generation of the Clec1btm1Ksi and Clec1btm1.1Ksi alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec1b Mutation:	17 strains or lines available

Original:	J:165898 Suzuki-Inoue K, et al., Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J Biol Chem. 2010 Aug 6;285(32):24494-507
All:	4 reference(s)