Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Col13a1tm3.1Pih
Name:	collagen, type XIII, alpha 1; targeted mutation 3.1, Taina Pihlajaniemi
MGI ID:	MGI:4838409
Synonyms:	Col13a1T
Gene:	Col13a1  Location: Chr10:61674015-61814887 bp, - strand  Genetic Position: Chr10, 32.29 cM, cytoband B4
Alliance:	Col13a1tm3.1Pih page

Germline Transmission:	Earliest citation of germline transmission: J:164671
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis on lung and femur extracts. (J:164671)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Col13a1 Mutation:	70 strains or lines available

Original:	J:164671 Latvanlehto A, et al., Muscle-derived collagen XIII regulates maturation of the skeletal neuromuscular junction. J Neurosci. 2010 Sep 15;30(37):12230-41
All:	5 reference(s)