Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Clcn5tm6.2Tjj
Name:	chloride channel, voltage-sensitive 5; targeted mutation 6.2, Thomas J Jentsch
MGI ID:	MGI:4834489
Gene:	Clcn5  Location: ChrX:7020049-7185597 bp, - strand  Genetic Position: ChrX, 3.21 cM, cytoband F3-F4
Alliance:	Clcn5tm6.2Tjj page

Germline Transmission:	Earliest citation of germline transmission: J:164474
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed exon 11 and 12. Western blot analysis confirmed the absence of protein expression. (J:164474)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clcn5 Mutation:	16 strains or lines available

Original:	J:164474 Rickheit G, et al., Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation. J Biol Chem. 2010 Jun 4;285(23):17595-603
All:	1 reference(s)