Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Macf1tm2.2Liem
Name:	microtubule-actin crosslinking factor 1; targeted mutation 2.2, Ronald K H Liem
MGI ID:	MGI:4831019
Synonyms:	Macf1R
Gene:	Macf1  Location: Chr4:123243426-123581331 bp, - strand  Genetic Position: Chr4, 57.42 cM
Alliance:	Macf1tm2.2Liem page

Germline Transmission:	Earliest citation of germline transmission: J:164146
Parent Cell Line:	CSL3 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed the neo cassette and exons 6 and 7. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:164146)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Macf1 Mutation:	853 strains or lines available

Original:	J:164146 Goryunov D, et al., Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain. Mol Cell Neurosci. 2010 May;44(1):1-14
All:	1 reference(s)