Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Anpeptm1.1Lsha
Name:	alanyl aminopeptidase, membrane; targeted mutation 1.1, Linda H Shapiro
MGI ID:	MGI:4830680
Synonyms:	CD13KO, Lap1tm1.1Lsha
Gene:	Anpep  Location: Chr7:79471551-79497958 bp, - strand  Genetic Position: Chr7, 45.19 cM
Alliance:	Anpeptm1.1Lsha page

Germline Transmission:	Earliest citation of germline transmission: J:163945
Parent Cell Line:	D1 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6J)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 4 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 13. Cre mediated recombination removed exon 4 through exon 13 as well as the neo cassette. The absence of protein expression was confirmed by western blot analysis on kidney, spleen, liver, and intestine extracts. (J:163945)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Anpep Mutation:	81 strains or lines available

Original:	J:163945 Winnicka B, et al., CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse. J Leukoc Biol. 2010 Aug;88(2):347-59
All:	8 reference(s)