Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tnfaip3tm1.2Gvl
Name:	tumor necrosis factor, alpha-induced protein 3; targeted mutation 1.2, Geert van Loo
MGI ID:	MGI:4829664
Gene:	Tnfaip3  Location: Chr10:18876658-18891158 bp, - strand  Genetic Position: Chr10, 8.08 cM
Alliance:	Tnfaip3tm1.2Gvl page

Germline Transmission:	Earliest citation of germline transmission: J:163410
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed exons 4 and 5. The absence of protein expression was confirmed by western blot analysis on colonic epithelial extracts. (J:163410)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfaip3 Mutation:	43 strains or lines available

Original:	J:163410 Vereecke L, et al., Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J Exp Med. 2010 Jul 5;207(7):1513-23
All:	2 reference(s)