Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Chdhtm1Zei
Name:	choline dehydrogenase; targeted mutation 1, Steven H Zeisel
MGI ID:	MGI:4822561
Gene:	Chdh  Location: Chr14:29730957-29762423 bp, + strand  Genetic Position: Chr14, 18.4 cM
Alliance:	Chdhtm1Zei page

Germline Transmission:	Earliest citation of germline transmission: J:162343
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The exons 1-3 of the gene was replaced with a neo cassette by targeted homologous recombination. (J:162343)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chdh Mutation:	37 strains or lines available

Original:	J:162343 Johnson AR, et al., Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J. 2010 Aug;24(8):2752-61
All:	2 reference(s)