Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ncoa3tm2.2Jxu
Name:	nuclear receptor coactivator 3; targeted mutation 2.2, Jianming Xu
MGI ID:	MGI:4462058
Synonyms:	SRC-3d
Gene:	Ncoa3  Location: Chr2:165834557-165915162 bp, + strand  Genetic Position: Chr2, 86.22 cM, cytoband H2-H4
Alliance:	Ncoa3tm2.2Jxu page

Germline Transmission:	Earliest citation of germline transmission: J:161101
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 11-12 were floxed and a FLP flanked Neo cassette was inserted within intron 17. The selection cassette and exons 11-12 were removed by flp and cre mediated recombination respectively. (J:161101)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ncoa3 Mutation:	231 strains or lines available

Original:	J:161101 Liu Z, et al., Generation and validation of a mouse line with a floxed SRC-3/AIB1 allele for conditional knockout. Int J Biol Sci. 2008;4(4):202-7
All:	1 reference(s)