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Sema6ctm1Matl
Targeted Allele Detail
Summary
Symbol: Sema6ctm1Matl
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C; targeted mutation 1, Marc Tessier-Lavigne
MGI ID: MGI:4461964
Gene: Sema6c  Location: Chr3:95067768-95081335 bp, + strand  Genetic Position: Chr3, 40.74 cM, cytoband F2
Alliance: Sema6ctm1Matl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161856
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA secretory gene trap cassette was inserted into intron 15 by the targeted trapping method. Absence of wild-type transcript was confirmed by Northern blot analysis of brain mRNA from 4 day old pups. (J:161856)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema6c Mutation:  43 strains or lines available
References
Original:  J:161856 Takamatsu H, et al., Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol. 2010 Jul;11(7):594-600
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory