Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Esr1tm1.1Rake
Name:	estrogen receptor 1 (alpha); targeted mutation 1.1, Ruth A Keri
MGI ID:	MGI:4461460
Synonyms:	Ex3alphaERKO
Gene:	Esr1  Location: Chr10:4561989-4955633 bp, + strand  Genetic Position: Chr10, 2.03 cM
Alliance:	Esr1tm1.1Rake page

Germline Transmission:	Earliest citation of germline transmission: J:161401
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Two loxP sites were inserted to flank Exon 3, the coding region for the DNA binding domain. Exon 3 was deleted by Cre-mediated recombination. (J:161401)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr1 Mutation:	67 strains or lines available

Original:	J:161401 Bernardo GM, et al., FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development. 2010 Jun;137(12):2045-54
All:	1 reference(s)