Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fastktm1.1Andp
Name:	Fas-activated serine/threonine kinase; targeted mutation 1, Paul Anderson
MGI ID:	MGI:4461026
Gene:	Fastk  Location: Chr5:24646036-24650280 bp, - strand  Genetic Position: Chr5, 11.78 cM, cytoband A3
Alliance:	Fastktm1.1Andp page

Germline Transmission:	Earliest citation of germline transmission: J:160443
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding sequence was replaced by a floxed neo cassette. The selection cassette was removed by cre mediated recombination. (J:160443)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fastk Mutation:	22 strains or lines available

Original:	J:160443 Simarro M, et al., Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. J Immunol. 2010 May 1;184(9):5325-32
All:	6 reference(s)