Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prss21tm1Anta
Name:	serine protease 21; targeted mutation 1, Toni M Antalis
MGI ID:	MGI:4397679
Gene:	Prss21  Location: Chr17:24087046-24092087 bp, + strand  Genetic Position: Chr17, 12.11 cM, cytoband A3.3-B
Alliance:	Prss21tm1Anta page

Germline Transmission:	Earliest citation of germline transmission: J:154521
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The genomic sequence spanning exon 4, 5, and the coding region of exon 6 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on testis extract. (J:154521)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prss21 Mutation:	13 strains or lines available

Original:	J:154521 Netzel-Arnett S, et al., The glycosylphosphatidylinositol-anchored serine protease PRSS21 (testisin) imparts murine epididymal sperm cell maturation and fertilizing ability. Biol Reprod. 2009 Nov;81(5):921-32
All:	1 reference(s)