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Slc13a2tm1Smch
Targeted Allele Detail
Summary
Symbol: Slc13a2tm1Smch
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2; targeted mutation 1, Stephen Chung
MGI ID: MGI:4360396
Synonyms: NaDC1-
Gene: Slc13a2  Location: Chr11:78288102-78313107 bp, - strand  Genetic Position: Chr11, 46.74 cM
Alliance: Slc13a2tm1Smch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152740
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 6 were replaced with a neo cassette. The absence of transcript expression was confirmed by northen blot analysis on kidney extracts and RT-PCR on kidney and small intestine extracts. (J:152740)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc13a2 Mutation:  43 strains or lines available
References
Original:  J:152740 Ho HT, et al., Generation and characterization of sodium-dicarboxylate cotransporter-deficient mice. Kidney Int. 2007 Jul;72(1):63-71
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory