Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Ghrtm1.2Masp Name: growth hormone receptor; targeted mutation 1.2, Mark A Sperling MGI ID: MGI:4359895 Gene: Ghr  Location: Chr15:3347237-3612834 bp, - strand  Genetic Position: Chr15, 1.84 cM Alliance: Ghrtm1.2Masp page

Small body size of Ghrtm1.2Masp/Ghrtm1.2Masp mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:152627
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Germ line, cre mediated recombination removed exon 4. (J:152627)

Generation of the Ghrtm1.1Masp and Ghrtm1.2Masp alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ghr Mutation:	49 strains or lines available

Original:	J:152627 Fan Y, et al., Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. J Biol Chem. 2009 Jul 24;284(30):19937-44
All:	2 reference(s)