Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nalcntm1.1Dren
Name:	sodium leak channel, non-selective; targeted mutation 1.1, Dejian Ren
MGI ID:	MGI:3819820
Gene:	Nalcn  Location: Chr14:123514046-123864556 bp, - strand  Genetic Position: Chr14, 66.04 cM
Alliance:	Nalcntm1.1Dren page

Germline Transmission:	Earliest citation of germline transmission: J:141581
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed by semi-quantitative RT-PCR on E18.5 brain extracts. (J:141581)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nalcn Mutation:	116 strains or lines available

Original:	J:141581 Lu B, et al., The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm. Cell. 2007 Apr 20;129(2):371-83
All:	4 reference(s)