Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rhcgtm1Ibmm
Name:	Rhesus blood group-associated C glycoprotein; targeted mutation 1, Claude Szpirer
MGI ID:	MGI:3818662
Gene:	Rhcg  Location: Chr7:79243111-79267405 bp, - strand  Genetic Position: Chr7, 45.09 cM
Alliance:	Rhcgtm1Ibmm page

Germline Transmission:	Earliest citation of germline transmission: J:141372
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An IRES-lacZ gene and a floxed neomycin resistance cassette replaced part of exon 3, exons 4-8, and part of exon 9. Founder mice were crossed with a cre-transgenic strain to removed the neomycin cassette. Gene inactivation was confirmed immunoblotting of male genital tract lysates from homozygous mice (J:141372)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rhcg Mutation:	20 strains or lines available

Original:	J:141372 Biver S, et al., A role for Rhesus factor Rhcg in renal ammonium excretion and male fertility. Nature. 2008 Nov 20;456(7220):339-43
All:	1 reference(s)