Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fads2tm1Wst
Name:	fatty acid desaturase 2; targeted mutation 1, Wilhelm Stoffel
MGI ID:	MGI:3814170
Gene:	Fads2  Location: Chr19:10040129-10078867 bp, - strand  Genetic Position: Chr19, 6.36 cM, cytoband B
Alliance:	Fads2tm1Wst page

Germline Transmission:	Earliest citation of germline transmission: J:140341
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The start codon of exon 1 was deleted and a pgk-neo cassette was inserted in exon 1 via homologous recombination. RT-PCR confirmed the absence of transcripts in all tissues examined. (J:140341)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fads2 Mutation:	19 strains or lines available

Original:	J:140341 Stoffel W, et al., Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. EMBO J. 2008 Sep 3;27(17):2281-92
All:	5 reference(s)