Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Ptk2btm1Okig
Name:	PTK2 protein tyrosine kinase 2 beta; targeted mutation 1, Mitsuhiko Okigaki
MGI ID:	MGI:3811004
Gene:	Ptk2b  Location: Chr14:66390706-66518501 bp, - strand  Genetic Position: Chr14, 34.36 cM
Alliance:	Ptk2btm1Okig page

Germline Transmission:	Earliest citation of germline transmission: J:139849
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin selection cassette was inserted in an unspecified exon. Absence of protein product was confirmed immunologically. (J:139849)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptk2b Mutation:	55 strains or lines available

Original:	J:139849 Matsui A, et al., Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function. Circulation. 2007 Aug 28;116(9):1041-51
All:	9 reference(s)