Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sfrp2tm1Ktas
Name:	secreted frizzled-related protein 2; targeted mutation 1, Kei Tashiro
MGI ID:	MGI:3810257
Gene:	Sfrp2  Location: Chr3:83673628-83681621 bp, + strand  Genetic Position: Chr3, 37.37 cM
Alliance:	Sfrp2tm1Ktas page

Germline Transmission:	Earliest citation of germline transmission: J:138805
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a neo cassette via homologous recombination. RT-PCR and in situ hybridization analysis confirmed the absence of transcript and protein in homozygotes. (J:138805)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp2 Mutation:	26 strains or lines available

Original:	J:138805 Ikegawa M, et al., Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice. Dev Dyn. 2008 Sep;237(9):2506-17
All:	1 reference(s)