About   Help   FAQ
Krt16tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Krt16tm1(KOMP)Vlcg
Name: keratin 16; targeted mutation 1, Velocigene
MGI ID: MGI:3808273
Synonyms: Krt16tm1Vlcg
Gene: Krt16  Location: Chr11:100136917-100139728 bp, - strand  Genetic Position: Chr11, 63.44 cM
Alliance: Krt16tm1(KOMP)Vlcg page
IMPC: Krt16 gene page
Mutation
origin
Mutant Cell Lines:  10501A-A5, 10501A-E2, 10501A-F2, 10501B-H1
Germline Transmission:  Earliest citation of germline transmission: J:184621
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2674bp between positions 100137040-100139713 of Chromosome 11 (Build GRCm39). (J:136110)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Krt16 Mutation:  28 strains or lines available
Notes
Mutant cell lines 10501A-E2 and 10501B-H1 have been used to generate chimeras but failed to establish germline transmission.
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory