Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tax1bp1tm1Ktj
Name:	Tax1 (human T cell leukemia virus type I) binding protein 1; targeted mutation 1, Kuan-Teh Jeang
MGI ID:	MGI:3808042
Gene:	Tax1bp1  Location: Chr6:52690714-52743765 bp, + strand  Genetic Position: Chr6, 25.7 cM
Alliance:	Tax1bp1tm1Ktj page

Germline Transmission:	Earliest citation of germline transmission: J:131849
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The translated region of exon 17 was replaced by a neomycin gene cassette. Western blot analysis indicated that no detectable protein was expressed from this allele. (J:131849)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tax1bp1 Mutation:	38 strains or lines available

Original:	J:131849 Iha H, et al., Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation. EMBO J. 2008 Feb 20;27(4):629-41
All:	4 reference(s)