Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Igkctm1Jkbv
Name:	immunoglobulin kappa constant; targeted mutation 1, Aya Jakobovits
MGI ID:	MGI:3802625
Synonyms:	deltaCkappa
Gene:	Igkc  Location: Chr6:70703419-70703738 bp, + strand  Genetic Position: Chr6, 32.04 cM, cytoband C
Alliance:	Igkctm1Jkbv page

Germline Transmission:	Earliest citation of germline transmission: J:23827
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     The Ckappa region was deleted to inactivate the mouse Igkappa locus. (J:23827)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igkc Mutation:	9 strains or lines available

Original:	J:23827 Green LL, et al., Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat Genet. 1994 May;7(1):13-21
All:	7 reference(s)