Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdh13tm1Brns
Name:	cadherin 13; targeted mutation 1, Barbara Ranscht
MGI ID:	MGI:3778287
Synonyms:	T-cadherin-, Tcad KO
Gene:	Cdh13  Location: Chr8:119010472-120051660 bp, + strand  Genetic Position: Chr8, 65.97 cM
Alliance:	Cdh13tm1Brns page

Germline Transmission:	Earliest citation of germline transmission: J:132759
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neo cassette was inserted into exon 5 that encodes the extracellular domain. The absence of protein product was confirmed by western blot analysis on fat pad extracts. (J:132759)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh13 Mutation:	30 strains or lines available

Original:	J:132759 Hebbard LW, et al., T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res. 2008 Mar 1;68(5):1407-16
All:	13 reference(s)