Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gper1tm1Cwan
Name:	G protein-coupled estrogen receptor 1; targeted mutation 1, Chunhe Wang
MGI ID:	MGI:3773753
Synonyms:	GPERKO
Gene:	Gper1  Location: Chr5:139408906-139413555 bp, + strand  Genetic Position: Chr5, 78.58 cM, cytoband G1
Alliance:	Gper1tm1Cwan page

Germline Transmission:	Earliest citation of germline transmission: J:131313
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on heart liver and kidney extracts. (J:131313)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gper1 Mutation:	27 strains or lines available

Original:	J:131313 Wang C, et al., GPR30 Contributes to Estrogen-Induced Thymic Atrophy. Mol Endocrinol. 2008 Mar;22(3):636-48
All:	30 reference(s)