Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trdntm1.1Cfp
Name:	triadin; targeted mutation 1.1, Claudio F Perez
MGI ID:	MGI:3769415
Synonyms:	Trdn-
Gene:	Trdn  Location: Chr10:32959479-33352705 bp, + strand  Genetic Position: Chr10, 18.37 cM, cytoband B1
Alliance:	Trdntm1.1Cfp page

Germline Transmission:	Earliest citation of germline transmission: J:128951
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A floxed neo cassette was inserted into the promoter region and an additional loxP site was inserted downstream of exon 1. Exon 1 and neo cassette were removed by germline cre-mediated recombination. The absence of protein product was confirmed by western blot on fast and slow twitch muscle extracts. (J:128951)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trdn Mutation:	59 strains or lines available

Original:	J:128951 Shen X, et al., Triadins modulate intracellular Ca2+ homeostasis but are not essential for excitation-contraction coupling in skeletal muscle. J Biol Chem. 2007 Dec 28;282(52):37864-74
All:	5 reference(s)