Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr299391tm1.1Fwa
Name:	regulatory region 299391; targeted mutation 1.1, Frederick W Alt
MGI ID:	MGI:3722842
Synonyms:	Edelta-, Edeltadelta, Tcrdtm1Fwa
Gene:	Rr299391  Location: Chr14:54375601-54376904 bp, . strand  Genetic Position: Chr14, Syntenic
Alliance:	Rr299391tm1.1Fwa page

Germline Transmission:	Earliest citation of germline transmission: J:55401
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutation:    Intergenic deletion   Mutation details: A 1085 bp region containing Tcrd enhancer Edelta was replaced with a loxP site flanked neomycin resistance gene cassette, which was subsequently removed via cre-mediated recombination. (J:55401)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr299391 Mutation:	0 strains or lines available

Original:	J:55401 Monroe RJ, et al., Developmental regulation of TCR delta locus accessibility and expression by the TCR delta enhancer. Immunity. 1999 May;10(5):503-13
All:	5 reference(s)