Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nmur1tm1Rtor
Name:	neuromedin U receptor 1; targeted mutation 1, Richard Torres
MGI ID:	MGI:3722111
Synonyms:	VG221
Gene:	Nmur1  Location: Chr1:86313964-86317083 bp, - strand  Genetic Position: Chr1, 43.94 cM, cytoband C5
Alliance:	Nmur1tm1Rtor page

Germline Transmission:	Earliest citation of germline transmission: J:124469
Parent Cell Line:	F1H4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NTac)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A LacZ gene and a floxed neomycin selection cassette were inserted in frame after amino acid 17, deleting sequences encoding amino acids 18 through 387. Quantitative RT- PCR on lung tissue failed to detect endogenous gene expression in homozygous mice. LacZ expression was not detected in homozygous mice. (J:102090, J:124469)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmur1 Mutation:	20 strains or lines available

Original:	J:124469 Torres R, et al., Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses. Pain. 2007 Aug;130(3):267-78
All:	3 reference(s)