Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Capn10tm1Ksp
Name:	calpain 10; targeted mutation 1, Kenneth S Polonsky
MGI ID:	MGI:3721096
Synonyms:	Capn10-
Gene:	Capn10  Location: Chr1:92862130-92875670 bp, + strand  Genetic Position: Chr1, 46.6 cM
Alliance:	Capn10tm1Ksp page

Germline Transmission:	Earliest citation of germline transmission: J:123988
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to delete exon 2. The vector included the self excising ACN cassette. Western blot confirmed absence of protein in mutants. (J:123988)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Capn10 Mutation:	26 strains or lines available

Original:	J:123988 Johnson JD, et al., RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 4;279(23):24794-802
All:	1 reference(s)