Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rab8atm1.2Aha
Name:	RAB8A, member RAS oncogene family; targeted mutation 1.2, Akihiro Harada
MGI ID:	MGI:3719354
Synonyms:	Rab8a-
Gene:	Rab8a  Location: Chr8:72915044-72935210 bp, + strand  Genetic Position: Chr8, 34.84 cM
Alliance:	Rab8atm1.2Aha page

Germline Transmission:	Earliest citation of germline transmission: J:123415
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Expression of cre recombinase in Rab8atm1Aha removed exon 2, causing a frame shift mutation and retaining the inactivated status of the original allele. (J:123415)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rab8a Mutation:	18 strains or lines available

Original:	J:123415 Sato T, et al., The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature. 2007 Jul 19;448(7151):366-9
All:	8 reference(s)