Summary | Mutation origin | Mutation description | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Adprhtm1Jlms
Name:	ADP-ribosylarginine hydrolase; targeted mutation 1, Joel Moss
MGI ID:	MGI:3719093
Synonyms:	Adprh-
Gene:	Adprh  Location: Chr16:38265761-38273051 bp, - strand  Genetic Position: Chr16, 26.86 cM, cytoband B4
Alliance:	Adprhtm1Jlms page

Germline Transmission:	Earliest citation of germline transmission: J:123619
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, including the critical catalytic site residues D60 and D61, was replaced with a neomycin resistance cassette. Transcript was not detected in mutant mice and immunoblotting confirmed absence of protein. (J:123619)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Adprhtm1Jlms

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adprh Mutation:	36 strains or lines available

Original:	J:123619 Kato J, et al., Enhanced sensitivity to cholera toxin in ADP-ribosylarginine hydrolase-deficient mice. Mol Cell Biol. 2007 Aug;27(15):5534-43
All:	5 reference(s)