Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Mllt1tm1Dw
Name:	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1; targeted mutation 1, Dennis Willerford
MGI ID:	MGI:3714136
Gene:	Mllt1  Location: Chr17:57199611-57242415 bp, - strand  Genetic Position: Chr17, 29.56 cM, cytoband E1.1
Alliance:	Mllt1tm1Dw page

Germline Transmission:	Earliest citation of germline transmission: J:108588
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Insertion of a neomycin resistance cassette into exon 6 results in a stop codon and is predicted to code for a truncated protein of less than 40% of mature size. (J:108588)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mllt1 Mutation:	21 strains or lines available

Original:	J:108588 Doty RT, et al., The leukemia-associated gene Mllt1/ENL: characterization of a murine homolog and demonstration of an essential role in embryonic development. Blood Cells Mol Dis. 2002 May-Jun;28(3):407-17
All:	1 reference(s)