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Pcyt2tm1Mbak
Targeted Allele Detail
Summary
Symbol: Pcyt2tm1Mbak
Name: phosphate cytidylyltransferase 2, ethanolamine; targeted mutation 1, Marica Bakovic
MGI ID: MGI:3711450
Synonyms: Pyct2-
Gene: Pcyt2  Location: Chr11:120500913-120508762 bp, - strand  Genetic Position: Chr11, 84.33 cM, cytoband E2
Alliance: Pcyt2tm1Mbak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121387
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1-3 were replaced with a neomycin resistance gene. (J:121387)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pcyt2 Mutation:  25 strains or lines available
References
Original:  J:121387 Fullerton MD, et al., Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2). Mol Cell Biol. 2007 May;27(9):3327-36
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory