Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cmahtm1Ykoz
Name:	cytidine monophospho-N-acetylneuraminic acid hydroxylase; targeted mutation 1, Yasunori Kozutsumi
MGI ID:	MGI:3711330
Synonyms:	Cmah-
Gene:	Cmah  Location: Chr13:24511387-24661272 bp, + strand  Genetic Position: Chr13, 10.34 cM, cytoband A3.2
Alliance:	Cmahtm1Ykoz page

Germline Transmission:	Earliest citation of germline transmission: J:121365
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a neo into the second coding exon. Western blot failed to detect protein in mutants. (J:121365)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cmah Mutation:	37 strains or lines available

Original:	J:121365 Naito Y, et al., Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Mol Cell Biol. 2007 Apr;27(8):3008-22
All:	10 reference(s)