Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr28tm1Msb
Name:	regulatory region 28; targeted mutation 1, Marisa S Bartolomei
MGI ID:	MGI:3701074
Synonyms:	H19Afp, H19tm6Msb
Gene:	Rr28  Location: unknown  Genetic Position: Chr7, Syntenic
Alliance:	Rr28tm1Msb page

Germline Transmission:	Earliest citation of germline transmission: J:118894
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to insert the alpha fetoprotein enhancer fragment and a floxed neomycin resistance gene cassette in place of the endodermal enhancers. Transient expression of cre recombinase removed the neo cassette. (J:118894)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr28 Mutation:	0 strains or lines available

Original:	J:118894 Verona RI, et al., Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression. Genomics. 2004 Jul;84(1):59-68
All:	1 reference(s)