Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Eps8tm1Ppdf Name: epidermal growth factor receptor pathway substrate 8; targeted mutation 1, Pier Paolo Di Fiore MGI ID: MGI:3693626 Synonyms: Eps8- Gene: Eps8  Location: Chr6:137454242-137626262 bp, - strand  Genetic Position: Chr6, 66.78 cM Alliance: Eps8tm1Ppdf page

Disorganized stereocilia in Eps8l2tm1Wma/Eps8l2tm1Wma Eps8tm1Ppdf/Eps8tm1Ppdf mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:116237
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin resistance cassette replaced one exon and part of a second exon. (J:116237)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eps8 Mutation:	123 strains or lines available

Original:	J:116237 Scita G, et al., EPS8 and E3B1 transduce signals from Ras to Rac. Nature. 1999 Sep 16;401(6750):290-3
All:	12 reference(s)