Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Rb1cc1tm1.3Guan
Name:	RB1-inducible coiled-coil 1; targeted mutation 1.3, Jun-Lin Guan
MGI ID:	MGI:3690329
Synonyms:	Fip200neo
Gene:	Rb1cc1  Location: Chr1:6284858-6346599 bp, + strand  Genetic Position: Chr1, 1.89 cM, cytoband A2
Alliance:	Rb1cc1tm1.3Guan page

Germline Transmission:	Earliest citation of germline transmission: J:114498
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Cre mediated excision resulted in the loss of floxed exons 4 and 5, leaving a floxed neo. (J:114498)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rb1cc1 Mutation:	82 strains or lines available

Original:	J:114498 Gan B, et al., Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol. 2006 Oct 9;175(1):121-33
All:	1 reference(s)