Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfkbibtm1Jpmz
Name:	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; targeted mutation 1, Joseph P Mizgerd
MGI ID:	MGI:3687303
Gene:	Nfkbib  Location: Chr7:28457676-28466069 bp, - strand  Genetic Position: Chr7, 16.91 cM, cytoband A3-B3
Alliance:	Nfkbibtm1Jpmz page

Germline Transmission:	Earliest citation of germline transmission: J:113618
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A sequence including nucleotides 253-987, over 60% of the coding region including the ankyrin repeats, was deleted from the locus. Western blot confirmed the absence of protein in lungs from mutant mice. (J:113618)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfkbib Mutation:	14 strains or lines available

Original:	J:113618 Mizgerd JP, et al., Functions of IkappaB proteins in inflammatory responses to Escherichia coli LPS in mouse lungs. Am J Respir Cell Mol Biol. 2002 Nov;27(5):575-82
All:	1 reference(s)