Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Rr100tm2Welm
Name:	regulatory region 100; targeted mutation 1, Wilfried Ellmeier
MGI ID:	MGI:3687192
Synonyms:	Cd8atm2Welm, N1delta2
Gene:	Rr100  Location: unknown  Genetic Position: Chr6, Syntenic
Alliance:	Rr100tm2Welm page

Germline Transmission:	Earliest citation of germline transmission: J:113136
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: ES cells containing the Rr98tm1Welm mutation were subsequently targeted with a vector replacing the Cd8a E8i enhancer element with a floxed neomycin resistance cassette. (J:113136)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr100 Mutation:	0 strains or lines available

Original:	J:113136 Ellmeier W, et al., Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression. Immunity. 2002 May;16(5):623-34
All:	1 reference(s)