Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Jam2tm1Okud
Name:	junction adhesion molecule 2; targeted mutation 1, Akihiko Okuda
MGI ID:	MGI:3663271
Gene:	Jam2  Location: Chr16:84571011-84622816 bp, + strand  Genetic Position: Chr16, 46.92 cM
Alliance:	Jam2tm1Okud page

Germline Transmission:	Earliest citation of germline transmission: J:112136
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exons 3-5 with an IRES-betageo cassette. Northern blot confirmed successful recombination in mutants, however, the production of some form of functional protein could not be eliminated. (J:112136)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Jam2 Mutation:	121 strains or lines available

Original:	J:112136 Sakaguchi T, et al., Putative 'stemness' gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol. 2006 Sep;26(17):6557-70
All:	2 reference(s)