Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ess2tm1Bld
Name:	ess-2 splicing factor; targeted mutation 1, Antonio Baldini
MGI ID:	MGI:3640092
Synonyms:	Es2el-
Gene:	Ess2  Location: Chr16:17718573-17729212 bp, - strand  Genetic Position: Chr16, 11.09 cM, cytoband B1-B3
Alliance:	Ess2tm1Bld page

Germline Transmission:	Earliest citation of germline transmission: J:57757
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector containing an Hprt3' selection cassette and a loxP site replaced a 200-bp fragment containing exon 4 of Es2el. The Es2eltm1Bld mutant allele was created in the double-targeted cell line 217 which was originally derived from AB2.2 ES cells J:57757. (J:57757)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ess2 Mutation:	28 strains or lines available

Original:	J:57757 Lindsay EA, et al., Congenital heart disease in mice deficient for the DiGeorge syndrome region [see comments]. Nature. 1999 Sep 23;401(6751):379-83
All:	1 reference(s)