Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Septin5tm1Bld
Name:	septin 5; targeted mutation 1, Antonio Baldini
MGI ID:	MGI:3640090
Synonyms:	Cdcrel1-, Cdcrel1tm1Bld
Gene:	Septin5  Location: Chr16:18440561-18448688 bp, - strand  Genetic Position: Chr16, 11.53 cM
Alliance:	Septin5tm1Bld page

Germline Transmission:	Earliest citation of germline transmission: J:67409
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2-4 of Sept5 were replaced with an Hprt3' chromosome engineering cassette in a targeting vector. AB2.2 embryonic stem cells that were double-targeted in trans were used to create knockout mice. (J:67409)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Septin5 Mutation:	27 strains or lines available

Original:	J:67409 Lindsay EA, et al., Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice. Nature. 2001 Mar 1;410(6824):97-101
All:	3 reference(s)