Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd248tm1Huso
Name:	CD248 antigen, endosialin; targeted mutation 1, David L Huso
MGI ID:	MGI:3625491
Gene:	Cd248  Location: Chr19:5118106-5120668 bp, + strand  Genetic Position: Chr19, 4.24 cM
Alliance:	Cd248tm1Huso page

Germline Transmission:	Earliest citation of germline transmission: J:107172
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced most of the single coding exon of the locus. RT-PCR confirmed absence of transcript in mutant colon, liver and skin samples. (J:107172)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd248 Mutation:	24 strains or lines available

Original:	J:107172 Nanda A, et al., Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3351-6
All:	12 reference(s)