Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gjd3tm1.2Kwi
Name:	gap junction protein, delta 3; targeted mutation 1.2, Klaus Willecke
MGI ID:	MGI:3624629
Synonyms:	Cx30.2LacZ
Gene:	Gjd3  Location: Chr11:98873006-98873842 bp, - strand  Genetic Position: Chr11, 62.89 cM
Alliance:	Gjd3tm1.2Kwi page

Germline Transmission:	Earliest citation of germline transmission: J:108288
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Cre mediated recombination removed the entire coding sequence. Endogenous protein was not detected, however immunostaining did detect LacZ expression. (J:108288)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gjd3 Mutation:	13 strains or lines available

Original:	J:108288 Kreuzberg MM, et al., Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5959-64
All:	4 reference(s)